日本細胞生物学会Japan Society for Cell Biology

日本細胞生物学会誌

The web site for "CSF"
-Cell Structure and Function-
published by "JSCB".
-Japan Society for Cell Biology-

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• 2023.9.14A new article was published in CSF.
  “VAMP5 and distinct sets of cognate Q-SNAREs mediate exosome release”
  This paper shows that a novel MVB-localized SNARE VAMP5 regulates exosome release through the MVB-plasma membrane fusion.
• 2023.7.22A new article was published in CSF.
  “FilGAP, a GAP for Rac1, down-regulates invadopodia formation in breast cancer cells”
  This paper shows that the RacGAP protein FilGAP is a negative regulator of invadopodia formation in breast cancer cells.
• 2023.7.12A new article was published in CSF.
  “Sphingomyelin metabolism underlies Ras excitability for efficient cell migration and chemotaxis”
  This paper shows sphingomyelin is an essential regulator of Ras excitability on the cell membrane that ensures efficient chemotaxis.
• 2023.6.30A new article was published in CSF.
  “Two coral fluorescent proteins of distinct colors for sharp visualization of cell-cycle progression”
  In this study, we have developed two fluorescent proteins of our own making to create Fucci5, which is free from license-related problems, in hopes of popularizing the Fucci technology in industry.
• 2023.6.27A new article was published in CSF.
  “Proteomic Analysis of Fatty Liver Induced by Starvation of Medaka Fish Larvae”
  This paper shows the mechanism of starvation-induced development of fatty liver in medaka fish larvae analyzed by proteomic analysis.
• 2023.5.11A new article was published in CSF.
  “Role of CRP2-MRTF interaction in functions of myofibroblasts”
  This paper shows that CRP2 plays a significant role in the functional expression of myofibroblasts by direct interaction between CRP2 and MRTF and reveals the detailed mechanism for CRP2-MRTF interaction.
• 2023.5.11A new article was published in CSF.
  “Zebrafish imaging reveals hidden oncogenic-normal cell communication during primary tumorigenesis”
  This review introduces the cooperative and competitive communication between oncogenic cells and neighboring cells, as revealed by our recent zebrafish imaging studies.
• 2023.4.6A new article was published in CSF.
  “Cell biology of protein-lipid conjugation”
  This review provides an overview of diverse forms of protein–lipid conjugation and summarizes the catalytic mechanisms and roles of these modifications.
• 2023.1.25A new article was published in CSF.
  “A conserved WXXE motif is an apical delivery determinant of ABC transporter C subfamily isoforms”
  This paper shows a stretch of four amino acid, WXXE motif, as the apical expression determinant of the 12-TM configuration ABCC subfamily members in polarized epithelial cells.
• 2022.12.28A new article was published in CSF.
  “Suppression of P-cadherin expression as a key regulatory element for embryonic stem cell stemness”
  This paper shows that spontaneously extruded syntaxin4 induces the expression of P-cadherin protein in 2D-ES cells, leading to the loss of ES cell stemness.
• 2022.12.28A new article was published in CSF.
  “A non-nucleotide agonist that binds covalently to cysteine residues of STING”
  This paper shows the identification of a novel STING agonist PAO, which does not target the cGAMP-binding pocket.
• 2022.12.16A new article was published in CSF.
  “Role of phosphatidylserine in the localization of cell surface membrane proteins in yeast”
  This paper shows requirement of phosphatidylserine in the localization of plasma membrane proteins such as receptors.
• 2022.12.16A new article was published in CSF.
  “Enhancement of Vivid-based Photo-Activatable Gal4 Transcription Factor in Mammalian Cells”
  This paper shows enhancement of Vivid-based blue light-activatable Gal4 transcription factor in mammalian cells to improve efficacy and reliability of optogenetic regulation of gene expressions.
• 2022.12.9A new article was published in CSF.
  “Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells”
  This paper shows that claudin-deficient MDCK cells can be used to reconstitute tight junctions and analyze their function by single subtypes of the claudin family.
• 2022.11.22A new article was published in CSF.
  “Quantitative 3D correlative light and electron microscopy of organelle association during autophagy”
  This study comprehensively analyzes the contacts between autophagosomes and other organelles by array tomography-based 3D-CLEM.
• 2022.11.5A new article was published in CSF.
  “PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis”
  This paper shows that PRL overexpression inhibits AMPK activation in kinetochores and causes mitotic errors.
• 2022.6.22A new article was published in CSF.
  “Appropriate tension sensitivity of α-catenin ensures rounding morphogenesis of epithelial spheroids”
  This paper shows the importance of the tension sensitivity of α-catenin in the rounding morphogenesis of epithelial spheroids.
• 2022.4.28A new article was published in CSF.
  “A method for the generation of pseudovirus particles bearing SARS coronavirus spike protein in high yields”
  This paper describes a modified protocol to generate pseudoviruses bearing SARS-CoV-2 spike protein in high yield.
• 2022.4.6A new article was published in CSF.
  “Munc13b stimulus-dependently accumulates on granuphilin-mediated, docked granules prior to fusion”
  This paper shows the mechanism by which granules docked to the plasma membrane fuse after stimulation by microscopic analyses in living cells.
• 2022.2.23A new article was published in CSF.
  “Ubiquitin-like 3 as a new protein-sorting factor for small extracellular vesicles”
  This review introduces the new concept of UBL3 as a post-translational modification factor that contributes to protein sorting to small extracellular vesicles (sEVs) and discusses cell biological functions and perspectives on the therapeutic application of UBL3.
• 2022.2.5A new article was published in CSF.
  “Specific association of TBK1 with the trans-Golgi network following STING stimulation”
  This paper shows that TBK1 associates with the trans-Golgi network following STING stimulation.
• 2021.11.6A new article was published in CSF.
  “A dual promoter system to monitor IFN-γ signaling in vivo at single-cell resolution”
  This paper shows a new fluorescence/bioluminescence IFN-γ reporter in cancer cells in vitro and in vivo.
• 2021.9.25A new article was published in CSF.
  “Visualization of DNA replication in single chromosome by stable isotope labeling”
  This paper shows the quantitative visualization of stable-isotope label with organelle-level resolution, and suggested the renewal of histone molecules in daughter chromosomes.
• 2021.9.4A new article was published in CSF.
  “In vivo roles of Rab27 and its effectors in exocytosis”
  This review provides a comprehensive summary of the in vivo functions of Rab27 and its effectors in exocytosis, and discuss the functional relationship among different effectors expressed in the same cells.
• 2021.9.3A new article was published in CSF.
  “Nuclear RNA regulation by XRN2 and XTBD family proteins”
  This paper reviews the functions of proteins that have XTBD, an evolutionarily conserved XRN2-binding domain, in regulation of nuclear RNA.
• 2021.6.30A new article was published in CSF.
  “Hrd1-dependent degradation of the unassembled PIGK subunit of the GPI transamidase complex”
  This paper shows that Hrd1 is required for the degradation of the unassembled PIGK subunit of the GPI transamidase complex.
• 2021.5.8A new article was published in CSF.
  “Expression Patterns and Levels of All Tubulin Isotypes Analyzed in GFP Knock-In C. elegans Strains”
  This paper describes a comprehensive analysis of expression patterns and levels of all α/β-tubulin isotypes in the nematode C. elegans.
• 2021.3.26A new article was published in CSF.
  “Multiple ways for stress sensing and regulation of the endoplasmic reticulum-stress sensors”
  This paper reviews the mechanisms through which ER stress-sensor proteins sense stressing stimuli and are activated.
• 2021.1.26A new article was published in CSF.
  “Knock-in of labeled proteins into 5’UTR enables highly efficient generation of stable cell lines”
  This paper shows an easy and efficient method to generate stable cell lines that express tagged proteins of interest at a physiological level.
• 2020.12.22A new article was published in CSF.
  “Mevalonate pathway-mediated ER homeostasis is required for haploid stability in human somatic cells”
  This study reveals the involvement of the mevalonate pathway in the stability of haploidy in human somatic cells through securing ER homeostasis.
• 2020.11.13A new article was published in CSF.
  “An antiviral drug screening platform with a FRET biosensor for measurement of arenavirus Z assembly”
  This paper shows the development of a novel FRET biosensor named Zabton to monitor the self-assembly of arena-viral Z protein. Zabton-based screening identifies a small chemical compound that inhibits arenavirus propagation.
• 2020.7.8A new article was published in CSF.
  “Prickle2 and Igsf9b coordinately regulate the cytoarchitecture of the axon initial segment”
  This paper shows that Prickle2 and Igsf9b coordinately regulate the cytoarchitecture of the axon initial segment.
• 2020.7.8A new article was published in CSF.
  “p18/Lamtor1-mTORC1 Signaling Controls Development of Mucin-producing Goblet Cells in the Intestine”
  This paper shows that p18/Lamtor1-mTORC1 signaling plays crucial roles in the development of mucin-producing intestinal goblet cells.
• 2020.6.25A new article was published in CSF.
  “Biliverdin reductase-A deficiency brighten and sensitize biliverdin-binding chromoproteins”
  This paper shows that biliverdin reductase-A deficiency augments the brightness of near-infrared fluorescence protein and photo-response of biliverdin-dependent optogenetic tools.
• 2020.6.24A new article was published in CSF.
  “Internalization of AMPA-type glutamate receptor in the MIN6 pancreatic β-cell line”
  This paper shows that an AMPA-type glutamate receptor is internalized in the MIN6 pancreatic beta cell line, and cortactin partially contributes to this process.
• 2020.6.18A new article was published in CSF.
  “Visualization of procollagen IV reveals ER-to-Golgi transport by ERGIC-independent carriers”
  This paper shows that procollagen IV is exported from the ER via a unique transport vesicle without recruitment of ER-Golgi intermediate compartment membranes.
• 2020.5.12A new article was published in CSF.
  “MON2 guides Wntless transport to the Golgi through recycling endosomes”
  The paper shows that the MON2 protein regulates formation and dynamics of recycling endosomes.
• 2020.4.9A new article was published in CSF.
  “Centrosomal and non-centrosomal functions emerged through eliminating centrosomes”
  This paper overviews cell biological findings revealed through various approaches for removing centrosomes from somatic cells.
• 2020.2.7A new article was published in CSF.
  “Rab7B/42 is functionally involved in protein degradation on melanosomes in keratinocytes”
  This paper shows that the small GTPase Rab7B (also called Rab42) promotes protein degradation on melanosomes in keratinocytes.
• 2019.12.27A new article was published in CSF.
  “Hierarchical development of motile polarity in durotactic cells just crossing an elasticity boundary”
  This paper reveals the actual time lag between generation of asymmetric activity of focal adhesions and formation of front-rear polarity in cell shaping in the durotactic cells just crossing an elasticity boundary.
• 2019.12.26A new article was published in CSF.
  “Development of a Rapid in vivo Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response using Medaka Fish”
  This paper shows development of a rapid in vivo assay to evaluate the efficacy of IRE1-specific inhibitors of the unfolded protein response using medaka fish.
• 2019.12.19A new article was published in CSF.
  “Reinvestigation of disulfide-bonded oligomeric forms of the unfolded protein response transducer ATF6”
  This paper shows that ER stress sensor ATF6 exists as monomer and two types of dimer, which are activated by single reduction of disulfide bond.
• 2019.11.30A new article was published in CSF.
  “N-glycosylation of Rim21 at an unconventional site fine-tunes its behavior in the plasma membrane”
  This paper suggests that N-linked glycosylation of Rim21 fine-tunes its localization to microdomains in the plasma membrane.
• 2019.11.15A new article was published in CSF.
  “Localization of BCR-ABL to stress granules contributes to its oncogenic function”
  This papers shows that BCR-ABL, a causative protein for CML, is localized in stress granules, and the granule localization is important for its oncogenicity.
• 2019.11.15A new article was published in CSF.
  “Folding latency of fluorescent proteins affects the mitochondrial localization of fusion proteins”
  This paper shows that the folding rate of fluorescent proteins affects the mitochondrial localization of the markers.
• 2019.10.17A new article was published in CSF.
  “Dispersion of endoplasmic reticulum-associated compartments by 4-phenyl butyric acid in yeast cells”
  This paper shows that, on yeast ER membrane, 4-PBA disperses transmembrane-protein aggregates, which then exert bad effects for cells.
• 2019.9.20A new article was published in CSF.
  “Moss Kinesin-14 KCBP Accelerates Chromatid Motility in Anaphase”
  This paper shows that moss kinesin KCBP supports chromatid segregation in mitosis.
• 2019.9.20A new article was published in CSF.
  “Implication of a Novel Function of Sar1 in the Nucleus”
  This paper shows a possible novel role of Sar1 within the nucleus, which may relate to the proper formation of the nuclear envelope.
• 2019.9.19A new article was published in CSF.
  “MGSE regulates crosstalk from the mucin pathway to the TFE3 pathway of the Golgi stress response”
  This paper revealed the mucin pathway, the novel response pathway of the mammalian Golgi stress response, and identified the enhancer element called MGSE.
• 2019.9.5A new article was published in CSF.
  “Mutations in mxc Tumor-Suppressor Gene Induce Chromosome Instability in Drosophila Male Meiosis”
  This paper describes the mechanism how a chromosome instability is given rise to during male meiosis in mutants of Drosophila tumor suppressor gene, mxc.
• 2019.8.31A new article was published in CSF.
  “Identification of 15 new bypassable essential genes of fission yeast”
  This paper presents the development of a bypass-of-essentiality screening in fission yeast.
• 2019.7.12A new article was published in CSF.
  “Organelle Zones”
  This is a review article on organelle zones.
• 2019.4.20 We have established our privacy policy.
• 2019.3.21A new article was published in CSF.
  “A peptide derived from phosphoinositide 3-kinase inhibits endocytosis and influenza virus infection”
  This paper identifies a peptide critical for endocytosis and influenza virus infection, and shows its potential for clinical application.
• 2019.3.21A new article was published in CSF.
  “Two decades of genetically encoded biosensors based on Förster resonance energy transfer”
  This paper overviews two decades of genetically encoded biosensors based on the principle of Förster resonance energy transfer.
• 2018.11.28A new article was published in CSF.
  “PGSE is a novel enhancer regulating the proteoglycan pathway of the mammalian Golgi stress response”
  This paper revealed the proteoglycan pathway, the novel response pathway of the mammalian Golgi stress response, and identified the enhancer element called PGSE.
• 2018.11.8A new article was published in CSF.
  “Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells”
  This paper shows that glycosphingolipid GM2 contributes to invasion in irradiation-tolerant lung cancer cells.
• 2018.7.26A new article was published in CSF.
  “An anti-tumorigenic role of the Warburg effect at emergence of transformed cells”
  This review article summarizes the novel role of the warburg-effect like metabolic changes to eliminate transformed cells from epithelia.
• 2018.7.26A new article was published in CSF.
  “Automatic quantitative segmentation of myotubes reveals single-cell dynamics of S6 kinase activation”
  This paper describes novel an automatic quantitative segmentation method of myotubes using fluorescent time-lapse images and demonstrates the different properties of S6K dynamics between myotube population and individuals.
• 2018.7.20A new article was published in CSF.
  “Branched sialylated N-glycans are accumulated in brain synaptosomes and interact with Siglec-H”
  This paper shows that branched sialylated N-glycans in synaptosomes play a role in the interaction of dendritic spines with microglia.
• 2018.7.13A new article was published in CSF.
  “Mesoporous Silica Nanoparticles Rescue H₂O₂-induced Inhibition of Cardiac Differentiation”
  This paper shows mesoporous silica nanoparticles exhibit protection against oxidative stress with respect to cardiac differentiation in human embryonic stem cells.
• 2018.6.29A new article was published in CSF.
  “A novel morphological marker for the analysis of molecular activities at the single-cell level”
  This paper shows a novel morphological marker for in vivo imaging and a method for analyzing the molecular activity in each cell by using machine learning.
• 2018.6.14A new article was published in CSF.
  “Detailed analysis of the interaction of yeast COG complex”
  This paper shows detailed analysis of the subunit interactions of the COG, tethering complex of the Golgi, in yeast.
• 2018.5.19A new article was published in CSF.
  “Long-term Culture of Human iPS Cell-derived Telencephalic Neuron Aggregates on Collagen Gel”
  This paper shows that human iPS cells derived telencephalic neuron aggregates can be cultured for a long time on collagen gel.
• 2018.4.28A new article was published in CSF.
  “Solo and keratin filaments regulate epithelial tubule morphology”
  This paper shows that Solo, a RhoA-targeting GEF, and keratin filaments are involved in the elongated morphology of epithelial tubules.
• 2018.4.11A new article was published in CSF.
  “Hidden Peptides Encoded by Putative Noncoding RNAs”
  This paper summarize the peptides that have been recently identified as translation products of putative ncRNAs.
• 2018.3.17A new article was published in CSF.
  “Live-cell imaging with genetically encoded protein kinase activity reporters”
  This paper reviews the principles and applications of fluorescence reporters to visualize the kinase activities in living cells.
• 2018.2.23A new article was published in CSF.
  “Structural Insights into the Altering Function of CRMP2 by Phosphorylation”
  This paper describes the alteration of CRMP2 function for the microtubule dynamics by using the biochemical and structural analyses.
• 2018.2.15A new article was published in CSF.
  “SPIRAL2 stabilises endoplasmic microtubule minus ends in the moss Physcomitrella patens”
  This paper shows that moss SPIRAL2 (SPR2) protein is specifically localised to and stabilises the minus end of endoplasmic microtubules in protonemal cells.
• 2018.2.2A new article was published in CSF.
  “A missense mutation in the NSF gene causes abnormal Golgi morphology in Arabidopsis thaliana”
  This paper describes isolation of an Arabidopsis mutant showing abnormal Golgi morphology and demonstrates that it is due to a missense mutation in the membrane fusion factor NSF.
• 2018.1.18A new article was published in CSF.
  “Intestinal epithelial cell-specific deletion of α-mannosidase II ameliorates experimental colitis”
  This paper shows the pathological role of intestinal epithelial cell-intrinsic α-mannosidase II in an animal model of inflammatory bowel disease.
• 2017.12.28A new article was published in CSF.
  “Flagellar-associated protein FAP85 is a microtubule inner protein that stabilizes microtubules”
  This paper shows that /Chlamydomonas /flagellar-associated protein FAP85 is one of the microtubule inner proteins (MIPs).
• 2017.10.25A new article was published in CSF.
  “Expression of Ror2 associated with fibrosis of the submandibular gland”
  This paper shows expression pattern of molecules, including Ror2 receptor tyrosine kinase, in an inflammatory model of the submandibular gland.
  “Bone marrow endothelial cells induce immature and mature B cell egress in response to erythropoietin”
  This paper shows that bone marrow endothelial cells, a component of hematopoietic microenvironments, promote B cell egress in response to erythropoietin during the early phase of anemia, thereby regulating emergency hematopoiesis.
• 2017.9.23A new article was published in CSF.
  “Deltamethrin increases neurite outgrowth in cortical neurons through endogenous BDNF/TrkB pathways”
  This paper shows that deltamethrin, a type 2 pyrethroid, enhances neurite outgrowth of cortical neurons via endogenous BDNF.
• 2017.8.31A new article was published in CSF.
  “The Position of the GFP Tag on Actin Affects the Filament Formation in Mammalian Cells”
  This paper shows that the fusion position of the GFP tag on actin affects the filament formation of actin.
• 2017.7.13A new article was published in CSF.
  “Drosophila DOCK family protein Zizimin involves in pigment cell differentiation in pupal retinae”
  This paper shows that Drosophila DOCK family protein Zizimin involves in piment cell differentiation in pupal retinae.
• 2017.7.11A new article was published in CSF.
  “Mitochondria regulate the differentiation of stem cells from human exfoliated deciduous teeth”
  This paper shows that increased mitochondrial activity was crucial for the neuronal differentiation of stem cells from human exfoliated deciduous teeth.
• 2017.5.26A new article was published in CSF.
  “SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation”
  This paper shows that SEL1L-dependent substrates require Derlin2/3 and Herp1/2, regardless of their soluble or transmembrane Nature, in endoplasmic reticulum-associated degradation.
• 2017.4.12A new article was published in CSF.
  “Synthesized Aβ42 Caused Intracellular Oxidative Damage, Leading to Cell Death, via Lysosome Rupture”
  This paper shows that synthesized Aβ42 caused lysosomal oxidative damage and rupture leading to cell death.
• 2017.4.4A new article was published in CSF.
  “The WD40 Domain of HIRA Is Essential for RI-nucleosome Assembly in Xenopus Egg Extracts”
  This paper shows that the WD40 domain of HIRA is essential for DNA replication-independent nucleosome assembly.
• 2017.3.18A new article was published in CSF.
  “4μ8C inhibits insulin secretion independent of IRE1α RNase activity”
  This paper shows that 4μ8C, an established inhibitor of IRE1α, has side-effects on insulin exocytosis.
• 2017.3.7A new article was published in CSF.
  “PI5P and PI(3,5)P₂: Minor, but Essential Phosphoinositides”
  This paper summarizes recent findings of the intracellular roles of phosphoinositides PI5P and PI(3,5)P2.
• 2017.2.7A new article was published in CSF.
  “TFE3, HSP47, and CREB3 pathways of the mammalian Golgi stress response”
  This review article summarized recent findings of the mammalian Golgi stress response.
• 2016.12.8A new article was published in CSF.
  “Improved FRET biosensor for the measurement of BCR-ABL activity in chronic myeloid leukemia cells”
  This paper reports on the development of an improved FRET biosensor for in vitro diagnostic to predict the efficacy of molecular targeted therapy against CML.
• 2016.11.23A new article was published in CSF.
  “A FRET biosensor for ROCK based on a consensus substrate sequence identified by KISS technology”
  This paper reports on the development of a FRET biosensor for Rho-associated protein kinase (ROCK), of which substrate peptide sequence has been determined by KISS technology.
• 2016.10.12A new article was published in CSF.
  “Pericentric H3K9me3 formation by HP1 interaction-defective histone methyltransferase Suv39h1”
  This paper shows the possibility that Suv39h1-mediated heterochromatin formation can be controlled by multiple modules, including HP1.
• 2016.9.29A new article was published in CSF.
  “Significance of extracellular vesicles: pathobiological roles in disease”
  This paper overviews resent knowledge regarding extracellular vesicles, such as microparticles/microvesicles, exosomes and apoptotic bodies, produced from various cells that are activated by environmental stimuli.
• 2016.9.8A new article was published in CSF.
  “Organization of non-centrosomal microtubules in epithelial cells”
  This article overviews recent progresses in the research on the mechanisms of non-centrosomal microtubule assembly in epithelial cells.
• 2016.7.2A new article was published in CSF.
  “Fertilization-independent cell-fusion between the synergid and central cell in the polycomb mutant”
  This paper shows fertilization-independent autonomous synergid-endosperm fusion in msi1, an Arabidopsis mutant of Polycomb Repressive Complex 2.
• 2016.6.2A new article was published in CSF.
  “MLX is a transcriptional repressor of the mammalian Golgi stress response”
  This paper shows that a transcription factor MLX negatively regulates the TFE3 pathway of the mammalian Golgi stress response.
• 2016.5.28A new article was published in CSF.
  “Multiplexed fluorescence imaging of ERK and Akt activities and cell-cycle progression”
  This paper shows the involvement of cell cycle-dependent regulation of ERK and Akt activities by using multiplexed fluorescence reporters.
• 2016.5.27A new article was published in CSF.
  “Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases”
  This is the first review article describing multiple types of GEFs for Rab small GTPases.
• 2016.2.4A new article was published in CSF.
  “Spätzle-processing enzyme-independent activation of the Toll pathway in Drosophila innate immunity”
  This paper shows the existence of a novel factor activating the Toll pathway in Drosophila.
• 2016.1.9A new article was published in CSF.
  “Atg101: not just an accessory subunit in the autophagy-initiation complex”
  This paper reviews the structure and function of the autophagy factor
  ATG101 that is not conserved in budding yeasts.
  “Shape and area of keratocytes are related to the distribution and magnitude of their traction forces”
  This paper shows that the shape of crawling cells, fish epidermal keratocytes, depends on the distribution of the traction forces, and that the magnitude of the traction forces depends on the area of the cells.
• 2015.12.22A new article was published in CSF.
  “Mechanism of the dendritic translation and localization of brain-derived neurotrophic factor”
  This paper shows that the specific 3’ UTR directs local translation of BDNF, which co-localizes with Bicaudal-D2 in neuronal dendrites.
• 2015.12.9A new article was published in CSF.
  “Yeast Ivy1p is a putative I-BAR-domain protein with pH-sensitive filament forming ability in vitro”
  This paper shows the pH-dependent polymerization of the yeast I-BAR domain protein Ivy1p.
• 2015.9.2We uploaded several experimental protocols from our society members. Please go to ‘Experimental protocol’ under ‘Experimental information’ on the left.
• 2015.7.22A new article was published in CSF.
  “Phosphoproteomic analysis using the WW and FHA domains as biological filters”
  This paper shows the novel focused phosphoproteomic approach to efficiently analyze intracellular phosphorylation signal networks.
• 2014.11.6Prof. Kazutoshi Mori was awarded the Albert Lasker Basic Medical Research Award 2014.